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PTO/SB/08a (08-03) 



lo persons am required to 



Application Number 



INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

(use as many sheets as necessary) 



First Named Inventor 



Examiner Name 



DEUTSCH Mordechai el 



EDWARDS LydiaE. 



Attomey Docket Number 



U.S. PATENT DOCUMENTS 



Pages, Columns, Lines, Where 
Relevant Passages or Relevant 
Figures Appear 



Cady ct al. 



FOREIGN PATENT DOCUMENTS 



Foreign Patent Documents 



wo 02/08748 
WO 99/66329 



23-Dec-1999 



Pages, Columns, Lines, 
Whare Relevant Passages 
or Relevant Figures Appear 



Examiner 
Signature 



Date 

Considered 



EXAMINER: Initial if reference considered, whether or not citation is in conformance with M 
Include copy of copy of this form with next communication to appUcant 

Applicant's unique citation designation number (optional). 
^ SeeKindsCodesofUSPTOPatentDocumentsatwww.uspto.gov or MPEP 901.04. 3 Enter 
^ Enter Office that issued the document, by the two-letter code (WlPO .Standard Sl'.3). 

For Japanese patent docmnents, die indicadon of the year of the reign of the Emperor must precede the serial mmiber 
^ Kind of document by the appropriate symbols as indicated on the document under WlPO Standard ST. 16 if possible. 

Applicant is to place a check mark here if English language translation is attached. 



line through citation if no 



n conformance and nc 



locument, by the two-letter code (WlPO Standard ST.3). 



1 applical 



122 ai 



form and/or suggestions for reducing fliis burden, should be sent to the Chief hiformation Officer, U.S. Patent and Trademark Office, U.S. 
1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissione 
Alexandria, VA 22313-1450 



ALL REFERENCES CONSIDERED EXCEPT WHERE LINED THROUGH. /LE./ 



PTO/SB/08a (08-03) 



Under the Paperwork Reduction Act of 199S, no persons are required to respond to a coUection of information unless it contains a valid OMB control number. 



Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

{use as many sheets as necessary) 


Complete if Known 


Application Number 


10/561,839 


Filing Date 


June 05, 2006 


First Named Inventor 


DEUTSCH Mordechai et al 


Group Art Unit 


1774 


Examiner Name 


EDWARDS Eydia E. 


Sheet 1 2 | Of | 2 


Attorney Docket Number 


30024 


OTHER PRIOR ART - NON PATENT LITERATURE DOCUMENTS 


Examiner 
Inilials 


Cite 

No/ 


Include name of the author (in CAPITAL UiTTERS), title of the article (when appropriate), title of the 
publisher, citj' and/or countiy where pubhshed. 


T^ 




4 


European Search Report and the European Seaich Opinion Dated 01 August 201 1 
From the European Patent Office Re. Application No. 10183774.8. 






5 


Gonzalez et al. "Cell-Based Assays and Instrumentation for Screening Ion-Channels 
Targets", Drug Discovery Today, DDT, XP001026838, 4(9): 431-439, 01 
September 1999. 





















Examiner 
Signature 


/Lydia Edwards/ 


Dale 

Considered 


10/11/2011 


' EXAMDTOR: Initial 




station is In conformance w 


itti MPEP 609. Draw Une ttffough citation if not in conform 


mce and not considered. 



Include copy of copy of this form with next communication to applicant. 
^ Applicant's unique citation designation nunibcr (optional). 

^ See. Kinds Codes of USPTO Patent Dociiments at www.uspto.gov or MPEP 901.04. 3 Enter OtHce that issued the document, by the two-letter code (WIPO Standard ST.3). 
^ Enler Office UiaL issued Uie docuiiienL, by die Lwo-lelLer code (WIPO Standard ST.3). 

For Japanese patent documents, the indication oft lie year of Che reign of the Emperor must precede the serial number of the patent document. 

Kind of document by the appropriate symbols as indicated on the document under WIPO Standard ST. 16 if possible. 

Applicant is to place a check mark here if English language translation is attached. 
Hiis collection of infomiation is required by 37 CER 1 .97 and 1.98. Tlie infomialion is required to obtain or retain a benefit by die public wliich is to file (and by tlie USPTO to 
process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. this collection is estimated to take 2 hours to complete, including gathering, preparing, and 
submitting die completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this 
form and/or suggestions for reducing this burden, should be sent to the Chief hiformadon Officer, U.S. Patent and Trademark Office, U.S. Department of commerce, P.O. Box 1450, 
Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.O. Box 1450, Alexandria, VA 
22313-1450 

If you need assistance In completing the form, call 1-800-PTO-9199 and select option 2. 



ALL REFERENCES CONSIDERED EXCEPT WHERE LINED THROUGH. /LE./